TEXAS CHILDREN'S LIVER CENTER
Biliary Atresia Clinic

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Within Texas Children's Liver Center, the Biliary Atresia Clinic provides comprehensive medical, surgical and transplant care for infants and children with biliary atresia. 

Biliary atresia is maldevelopment or blockage of the biliary system, a network of tubular structures and tiny ducts that drain bile from the liver to the small intestine where it aids in the digestive process. Biliary atresia affects only newborns and is not hereditary, contagious or preventable.

Biliary atresia is a progressive inflammatory condition that begins very soon after birth. In the most common form, extrahepatic biliary atresia, the ducts outside the liver are affected first. White blood cells invade the ducts, which become damaged and may wither or disappear. Bile is trapped inside the liver and rapidly causes damage and scarring to the liver cells. Further scarring of the liver may result in cirrhosis and liver failure.

Approximately one case of biliary atresia occurs in every 15,000 live births. In the United States, approximately 300 new cases are diagnosed each year. Texas Children's Liver Center physicians and surgeons have diagnosed and treated the most complex and rare cases involving biliary atresia in the nation.

Cutting-edge clinical research

Texas Children's Liver Center is among a handful of centers in the nation that participates in National Institutes of Health-funded protocols, including:

> BARC (Biliary Atresia Research Consortium)

> CHILDREN (Childhood Liver Disease Research and Education Network)

> Omegaven fish oil emulsion for TPN-associated liver disease

> SPLIT  (Studies of Pediatric Liver Transplantation)

> PALF (Pediatric Acute Liver Failure Study)

> Therapy of PTLD

> Fatty liver disease

> Parenteral nutrition-associated cholestasis

> Cystic Fibrosis-associated liver disease

For more information about participating in one of these clinical trials, contact us.